Vol. 16 No. 1 (2025)
Short Communications

Evaluation of Quality of Life in Patients on Different Treatment Modalities for Primary Glaucoma in a Tertiary Care Teaching Hospital- A Prospective Observational Study

PDF
  • Hirva Santoki,
  • Nishant B. Prajapati,
  • Reema Raval,
  • Kintu Shah,
  • Hemant Tiwari,
  • Shikha V. Sood
Hirva Santoki
Resident doctor, Department of Pharmacology, Smt. N.H.L. Municipal Medical College, Ahmedabad, Gujarat, India
Nishant B. Prajapati
Resident doctor, Department of Pharmacology, Smt. N.H.L. Municipal Medical College, Ahmedabad, Gujarat, India
Reema Raval
Associate Professor, Department of Ophthalmology, C.H. Nagri Eye Hospital, Ahmedabad, India
Kintu Shah
Associate Professor, Department of Ophthalmology, C.H. Nagri Eye Hospital, Ahmedabad, India
Hemant Tiwari
Assistant Professor (statistics), Department of Preventive and Social Medicine, Smt. N.H.L. Municipal Medical College, Ahmedabad, India
Shikha V. Sood
Associate Professor, Department of Pharmacology, Smt. N.H.L. Municipal Medical College, Ahmedabad, Gujarat, India
Categories

Published 31-03-2025

Keywords

  • NEI-VFQ-25,
  • Primary glaucoma,
  • Quality of life

Copyright (c) 2025 Hirva Santoki, Nishant B. Prajapati, Reema Raval, Kintu Shah, Hemant Tiwari, Shikha V. Sood (Author)

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

How to Cite

1.
Santoki H, Prajapati NB, Raval R, Shah K, Tiwari H, Sood SV. Evaluation of Quality of Life in Patients on Different Treatment Modalities for Primary Glaucoma in a Tertiary Care Teaching Hospital- A Prospective Observational Study. Healthline. 2025;16(1):67-71. doi:10.51957/Healthline_696_2025

Abstract

Introduction: Glaucoma, causes irreversible vision loss, involves optic nerve damage due to increased aqueous outflow resistance in primary open-angle glaucoma (POAG) or iris blockage in primary-angle closure glaucoma (PACG). Objective: This study evaluates different treatment patterns and their effectiveness in primary glaucoma using the NEI VFQ-25. Method: A 2-month prospective observational study included patients with primary glaucoma, excluding those with secondary glaucoma or other ocular conditions. The sample size was determined based on study duration. Treatment groups received medical, laser, or surgical interventions, alone or combined. NEI VFQ-25 was administered at baseline and one month. Results: Among 100 patients, mean age 56.7 years, equally divided between POAG and PACG, QoL improved significantly across all treatment groups, greatest in medical treatment alone, multimodal treatment, least. One-way ANOVA showed difference in treatment approach on outcomes. Conclusion: Using NEI-VFQ-25, study assessed QoL in glaucoma patients across six treatment groups, finding highest QoL with medical therapy alone and lowest with combined treatments.

PDF

References

  1. 1. Weinreb RN, Aung T, Medeiros FA. The pathophysiology and treatment of glaucoma: a review. JAMA. 2014 May 14;311(18):1901-11. doi: 10.1001/jama.2014.3192. PMID: 24825645; PMCID: PMC4523637. doi: 10.1001/jama.2014.3192
  2. 2. Conlon R, Saheb H, Ahmed II. Glaucoma treatment trends: a review. Can J Ophthalmol. 2017 Feb;52(1):114-124. doi: 10.1016/j.jcjo.2016.07.013. Epub 2016 Nov 17. PMID: 28237137. DOI: 10.1016/j.jcjo.2016.07.013
  3. 3. Runjić T, Novak Lauš K, Vatavuk Z. Effect of Different Visual Impairment Levels on the Quality of Life in Glaucoma Patients. Acta Clin Croat. 2018 Jun;57(2):243-250. doi: 10.20471/acc.2018.57.02.03. PMID: 30431716; PMCID: PMC6531995. doi: 10.20471/acc.2018.57.02.03
  4. 4. Francis BA, Minckler DS, Dustin L, et al. A comparison of glaucoma drainage devices with trabeculectomy in the treatment of refractory glaucoma. Ophthalmology. 2004;111(1):79-85. doi: 10.1097/APO.0000000000000452
  5. 5. Muralidharan S, Kumar S, Ichhpujani P, Dhillon HK. Quality of life in glaucoma patients: Comparison of medical therapy, trabeculectomy, and glaucoma drainage device surgery. Indian J Ophthalmol2022;70:4206-11. DOI: 10.4103/ijo.IJO_667_22
  6. 6. Seth PK, Senthil S, Das AV, Garudadri C. Prevalence of glaucoma types, clinical profile and disease severity at presentation: Tertiary Institute based cross-sectional study from South India. Indian Journal of Ophthalmology. 2023 Oct 1;71(10):3305-12. DOI: 10.4103/IJO.IJO_3305_22
  7. 7. Cohen LP, Pasquale LR. Clinical characteristics and current treatment of glaucoma. Cold Spring Harbor perspectives in medicine. 2014 Jun 1;4(6):a017236. DOI: 10.1101/cshperspect.a017236
  8. 8. Khurana AK. Comprehensive Ophthalmology. 8th ed. New Delhi: Jaypee Brothers Medical Publishers; 2019
  9. 9. Meesala A, Tripathy R, Chaudhury H, et al. (October 09, 2023) A Drug Utilization Study of Anti-glaucoma Drugs in a Tertiary Care Hospital. Cureus 15(10): e46765. DOI 10.7759/cureus.46765 doi: 10.7759/cureus.46765
  10. 10. Gedde SJ, Lind JT, Wright MM, Chen PP, Muir KW, Vinod K, Li T, Mansberger SL. Primary open-angle glaucoma suspect preferred practice pattern®. Ophthalmology. 2021 Jan 1;128(1):P151-92. DOI: 10.1016/j.ophtha.2020.10.023
  11. 11. Mohan N, Chakrabarti A, Nazm N, Mehta R, Edward DP. Newer advances in medical management of glaucoma. Indian journal of ophthalmology. 2022 Jun 1;70(6):1920-30. DOI: 10.4103/ijo.IJO_2239_21
  12. 12. Pastore MR, Milan S, Agolini R, Egidi L, Agostini T, Belfanti L, Cirigliano G, Tognetto D. How Could Medical and Surgical Treatment Affect the Quality of Life in Glaucoma Patients? A Cross-Sectional Study. Journal of Clinical Medicine. 2022 Dec 8;11(24):7301. doi: 10.3390/jcm11247301