Quality of Life among Patients with Neuropathic Pain Attending Outpatient Department of a Tertiary Care Hospital, Kolkata, India
DOI:
https://doi.org/10.51957/Healthline_765_2025Keywords:
Neuropathic pain, Psychological domain, Quality of lifeAbstract
Introduction: Neuropathic pain is a complex, painful condition, difficult to diagnose and treat with a negative impact on patients’ health and quality of life. Objectives: To evaluate the correlation between neuropathic pain and quality of life along with identifying the limiting aspects in the daily life of the patients suffering from it; and also, to find out association of socio-demographic factors with quality of life. Methods: A cross-sectional study was conducted for 3 months among 404 patients with neuropathic pain attending the outpatient department of Neuro-medicine and Physical medicine of a tertiary care teaching Hospital, Kolkata using WHO QOL-BREF Scale. Data were tabulated in MS-Excel spreadsheet, statistical analysis was done in SPSS version 26. Results: Among the study participants 264 (65.4%) were female, about 252 (62.2%) were Muslim and 372 (92.2%) were married. More than half of the study participants had poor quality of life 238 (59%) with burning 343 (93%), tingling 365 (90%) sensation. A total of 290 (72%) of the study participants were suffering from severe pain. It was found that the limiting aspect was the psychological domain. Significant association (p<0.05) was seen with age, gender, religion and education with QOL. Conclusion: Majority of the study participants had poor quality of life (59%) with the greatest impact on psychological domain after the onset of pain and presented a positive attitude for treatment towards it.
References
1. Shirley A, Abrahao Fontes Baptista, Mendes L, Kamilla Soares Silva, Cristine, Manoela F, et al. Impact of Neuropathic Pain at the Population Level. Journal of Clinical Medicine Research [Internet]. 2023 [cited 2024 Aug 7];6(2):111–9.
2. Moher D. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. Annals of Internal Medicine. 2019 Aug 18;151(4):264. DOI: https://doi.org/10.7326/0003-4819-151-4-200908180-00135
3. Almeida FC, Castilho A, Cesarino CB, Ribeiro R de CHM, Martins MRI. Correlation between neuropathic pain and quality of life. Brazilian Journal Of Pain. 2018;1(4). DOI: https://doi.org/10.5935/2595-0118.20180066
4. Ziegler D. Thioctic Acid for Patients with Symptomatic Diabetic Polyneuropathy. Treatments in Endocrinology. 2004;3(3):173–89. DOI: https://doi.org/10.2165/00024677-200403030-00005
5. Burgess J, Frank B, Marshall A, Khalil RS, Ponirakis G, Petropoulos IN, et al. Early Detection of Diabetic Peripheral Neuropathy: A Focus on Small Nerve Fibres. Diagnostics. 2021 Jan 24;11(2):165 DOI: https://doi.org/10.3390/diagnostics11020165
6. Baron R, Maier C, Attal N, Binder A, Bouhassira D, Cruccu G, et al. Peripheral neuropathic pain. PAIN. 2017 Feb;158(2):261–72. DOI: https://doi.org/10.1097/j.pain.0000000000000753
7. World Health Organization. WHOQOL - Measuring Quality of Life [Internet]. World Health Organization. 2012. Available from: https://www.who.int/tools/whoqol
8. Trust R. Website [Internet]. ePROVIDE - Mapi Research Trust. 2025 [cited 2025 Oct 24].
9. Visual Analogue Scale. (2024, August 5). Physiopedia. from https://www.physio-pedia.com/index.php?title=Visual_Analogue_Scale&oldid=356879.
10. Michigan Body Map (MBM) | Pain Research | Michigan Medicine [Internet]. Pain Research. 2016. Available from: https://medicine.umich.edu/dept/pain-research/clinical-research/michigan-body-map-mbm
11. World Health Organization. WHOQOL - Measuring Quality of Life| The World Health Organization [Internet]. www.who.int. 2012. Available from: https://www.who.int/tools/whoqol
12. Ansari D, Tingstedt B, Andersson B, Holmquist F, Sturesson C, Williamsson C, et al. Pancreatic cancer: yesterday, today and tomorrow. Future Oncology. 2016 Aug;12(16):1929–46. DOI: https://doi.org/10.2217/fon-2016-0010
13. Jensen MP, Chodroff MJ, Dworkin RH. The impact of neuropathic pain on health-related quality of life: Review and implications. Neurology. 2007 Apr 9;68(15):1178–82.1. DOI: https://doi.org/10.1212/01.wnl.0000259085.61898.9e
14. Toth C, Lander J, Wiebe S. The Prevalence and Impact of Chronic Pain with Neuropathic Pain Symptoms in the General Population. Pain Medicine. 2009 Jul;10(5):918–29.1. DOI: https://doi.org/10.1111/j.1526-4637.2009.00655.x
15. Harifi G, Amine M, Ait Ouazar M, Boujemaoui A, Ouilki I, Rekkab I, et al. Prevalence of Chronic Pain with Neuropathic Characteristics in the Moroccan General Population: A National Survey. Pain Medicine. 2013 Feb;14(2):287–92. DOI: https://doi.org/10.1111/pme.12009
16. Bouhassira D, Lanteri-Minet M, Attal N, Laurent B, Touboul C. Prevalence of chronic pain with neuro-pathic characteristics in the general population. Pain. 2008;136(3):380-387 DOI: https://doi.org/10.1016/j.pain.2007.08.013
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